採用情報
ラボラトリー
国立大学法人 群馬大学
JREC-IN

海外ラボラトリー

ハーバード大・マサチューセッツ総合病院

English
Kathryn D. Held
(PI)

MGH とは

MGH(マサチューセッツ総合病院)は、HMS(ハーバードメディカルスクール=ハーバード大学 医学系大学院)にとって最古で最大規模の教育研究病院であり、200年近い協力関係にある。また、MGH所属の多くの医師・研究者が、HMSにおいても教員の地位を持っている。 MGHは、全米で3番目に古い総合病院で、全米病院ランキングのトップ5に継続的に入っている。(US News & World Report)

研究内容

近年、放射線治療・診断の医療被ばくの影響や、有人宇宙飛行に対する宇宙放射線の影響など低線量放射線によるリスク評価に注目が集まっています。我々は、神経細胞を含む正常細胞およびがん細胞を用いて、低線量放射線による生物影響の一端を明らかにすることを目指しています。
なかでも、照射細胞だけでなく、その周辺の非照射細胞にも細胞間シグナル伝達を介して放射線影響が生じる「バイスタンダー効果」は、低線量放射線の生物影響を把握する上で、非照射細胞に着目した解析研究が重要であることを示してきました。我々は、重粒子線(もしくはX線)で誘発されたバイスタンダー効果の応答メカニズムを明らかにするため、細胞周期とDNA修復動態の関連に着目して解析を実施しています。

主要実績(論文、学会発表、受賞など)

・Niimi A, Yamauchi M, Limsirichaikul S, Sekine R, Oike T, Sato H, Suzuki K, Held KD, Nakano T, Shibata A. Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation. Genes Chromosomes Cancer 2016 Aug;55(8):650-60.

・Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. A new system for three-dimensional clinostat synchronized X-irradiation with a high-speed shutter for space radiation research. Biol Sci Space 2016; 30:8-16.

・Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system. Life Sci Space Res (Amst). 2017 Feb; 12:51-60.

・Performance evaluation of new devices to synchronize heavy-ion or X-ray irradiation and simulated microgravity for space radiation research ~ Improvement of a control stage ~; Akihisa Takahashi, Hiroko Ikeda, Hikaru Souda, Anggraeini Puspitasari, Kathryn D. Held, Jun Hidema, Takeshi Nikawa, Yukari Yoshida, and Tatsuaki Kanai; International Symposium on Space Technology and Science, Proceeding, Theses ID; 2017-p-09.

・Held KD, Kawamura H, Kaminuma T, Paz AE, Yoshida Y, Liu Q, Willers H, Takahashi A. Effects of charged particles on human tumor cells. Front Oncol 2016 Feb 12; 6:23.

・Held, KD. Integrating physics, chemistry, molecular and cellular biology, and human studies in radiation research, The 4th International Symposium of Gunma University Initiative for Advanced Research (GIAR), November 7th 2017.

・Held, KD, Special lecture at The 5th International Symposium of Gunma University Program for Leading Graduate Schools, Maebashi, Gunma, Japan. November 2nd – 3rd, 2017.

・Anggraeini Puspitasari, Noriko Koganezawa, Hidemasa Kawamura, Hiroyuki Yamazaki, Akihisa Takahashi, Tomoaki Shirao, Takashi Nakano, Kathryn D Held. “The effect of X-irradiation on neuronal function”. The 23rd Annual Meeting of International Association for the sensitization of Cancer Treatment, in KARUIZAWA, July 2017. Symposium.

・Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, “Performance evaluation of new devices to synchronize X-ray or heavy-ion irradiation and simulated microgravity for space radiation research”, 31st International Symposium on Space Technology and Science, Matsuyama, Japan, June 2017.

・Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, “New devices to synchronize irradiation and simulated µG for space radiation research”, The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), Suzhou, China, May 2017.

・Anggraeini Puspitasari, Noriko Koganezawa, Tomoaki Shirao, Kathryn D Held. “Effect of Radiation on Higher Brain Function: Neuroscience’s Investigation”. International Workshop of Gunma University Program for Leading Graduate Schools at Tojo-hall Gunma University on Feb 8, 2017 (invited); Educational.

・Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, Takahashi A. Gene expression profile changes of human fibroblasts using device to synchronize carbon-ion irradiation and simulated microgravity. Talk presented by Dr. Ikeda at the 5th International Symposium on Space Radiation and Particle Radiotherapy, Suzhou, China, May 2017.

・Puspitasari A, Koganezawa N, Shirao T, Kojima N, Held KD, Takahashi A, Nakano T. Acute effects of low-LET and high-LET radiation on fear memory formation and its underlying mechanisms. Talk presented by Dr. Puspitasari at the 5th International Symposium on Space Radiation and Particle Radiotherapy, Suzhou, China, May 2017.

・Puspitasari A, Kawamura H, Takahashi A, Yoshida Y, Shirao T, Nakano T, Held KD. Acute and chronic effects of low dose of X-irradiation on immature hippocampal neurons in vitro. Poster presented by Dr. Puspitasari at the 7th International Society of Radiation Neurobiology Conference, Yuzawa, Japan, February 2017.

・Puspitasari A, Kawamura H, Held KD, Shirao T, Nakano T. The radiation-induced bystander effects on synaptic function of mature neurons. Poster presented by Dr. Puspitasari at the 62nd Annual Meeting of the Radiation Research Society, Hawaii, October 2016.

・Held KD. Radiation effects on normal brain: Concerns for radiation therapy and space missions. Invited talk presented at the 6th International Society of Radiation Neurobiology (ISRN) Conference, Nagasaki, Japan, February 2016.

・Held KD. International research collaborations in radiation research for cancer therapy and space exploration. Invited talk presented at the 28th Annual meeting of the Japanese Society for Radiation Oncology (JASTRO), Gunma, Japan, November 2015.

・Held KD. Recent findings of radiation biology research. Invited educational seminar presented at 12th International Stereotactic Radiosurgery Society Congress, Yokohama, Japan, June 2015.

・Held, KD. Charged particle radiobiology research at MGH and thoughts on research at GIAR. Invited talk presented at the 1st International Symposium of Gunma University Initiative for Advanced Research, February, 2015.


Anggraeini PUSUPITASARI
職名:助教

主要実績(論文、学会発表、受賞など)

・X Irradiation Induces Acute Cognitive Decline via Transient Synaptic Dysfunction, Anggraeini Puspitasari, Noriko Koganezawa, Yuta Ishizuka, Nobuhiko Kojima, Natsume Tanaka, Takashi Nakano and Tomoaki Shirao, Radiation Research Apr 2016, Vol. 185, No. 4 (April 2016) pp. 423-430 (presence of peer review).

・A New System for Three-dimensional Clinostat Synchronized X-irradiation with a High-speed Shutter for Space Radiation Research, Hiroko Ikeda, Hikaru Souda, Anggraeini Puspitasari, Kathryn D. Held, Jun Hidema, Takeshi Nikawa, Yukari Yoshida, Tatsuaki Kanai, Akihisa Takahashi, Biological Sciences in Space, 2016.12.19.

・Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system, Hiroko Ikeda, Hikaru Souda, Anggraeini Puspitasari, Kathryn D. Held, Jun Hidema, Takeshi Nikawa, Yukari Yoshida, Tatsuaki Kanai, Akihisa Takahashi, Life Sciences in Space Research, 2017.1.21.

・Performance evaluation of new devices to synchronize heavy-ion or X-ray irradiation and simulated microgravity for space radiation research ~ Improvement of a control stage ~; Akihisa Takahashi, Hiroko Ikeda, Hikaru Souda, Anggraeini Puspitasari, Kathryn D. Held, Jun Hidema, Takeshi Nikawa, Yukari Yoshida, and Tatsuaki Kanai; International Symposium on Space Technology and Science, Proceeding, Theses ID; 2017-p-09.

・Shuchuan Miao, Noriko Koganezawa, Kenji Hanamura, Anggraeini Puspitasari, Tomoaki Shirao “N-Methyl-D-aspartate receptor mediates X-irradiation-induced drebrin decrease in hippocampus.” Kitakanto Medical Journal, in press (2018).

・Ingrid S Surono M.Sc, PhD., Priyo Waspodo, M.Sc., Anggraeini Puspitasari M.D, Ph.D., KARBOHIDRAT UNTUK PENDERITA DIABETES, book published in January 2018.

・Oral Presentation on International Symposium on Probiotic from Asian Traditional Fermented Foods for Healthy Gut Function Sari Pan Pacific Hotel, Indonesia, 19 – 20 August 2008, Tittle: Displacement and inhibition of Bacteroides vulgatus by Probiotic Bacteria

・13/1/25 – 1/26, The 3rd International Society of Radiation Neurobiology Conference

・13/10/29-10/31, Brain and Health Informatics. [Time-dependent effect of X-irradiation on fear conditioning and synaptic protein].

・14/01/24, The 2nd International Symposium of Gunma University Program for Leading Graduate Schools, Tittle: Early effects of X-irradiation on learning and synaptic proteins.

・15/09/11 – 13, The 58th Annual Meeting of the Japanese Society for Neurochemistry, Omiya, Saitama, Japan. [The acute immediate effect of X-irradiation and Carbon ion-irradiation on synaptic function and fear memory formation.]

・Anggraeini Puspitasari. “What is the radiation-induced bystander effect? From the point of view of Neurons and Glia” The 3rd International Symposium of Gunma University Initiative for Advanced Research (GIAR); Gunma, Japan. October 2016. Symposium.

・Anggraeini Puspitasari, Noriko Koganezawa, Tomoaki Shirao, Kathryn D Held. “Effect of Radiation on Higher Brain Function: Neuroscience’s Investigation”. International Workshop of Gunma University Program for Leading Graduate Schools at Tojo-hall Gunma University on Feb 8, 2017 (invited); Educational.

・Anggraeini Puspitasari, Noriko Koganezawa, Tomoaki Shirao, Nobuhiko Kojima, Kathryn D Held, Akihisa Takahashi, and Takashi Nakano. “Acute effects of low-LET and high-LET radiation on fear memory formation and its underlying mechanisms”. The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), which will be held in Suzhou, China, on May 24-26, 2017. Symposium.

・Anggraeini Puspitasari, Noriko Koganezawa, Hidemasa Kawamura, Hiroyuki Yamazaki, Akihisa Takahashi, Tomoaki Shirao, Takashi Nakano, Kathryn D Held. “The effect of X-irradiation on neuronal function”. The 23rd Annual Meeting of International Association for the sensitization of Cancer Treatment, in KARUIZAWA, July 15th 2017. Symposium.

・Anggraeini Puspitasari, “Excellent program and mentors lead to the beginning of carrier”. The 5th International Symposium of Gunma University Program for Leading Graduate Schools, Maebashi, Gunma, Japan. November 2nd – 3rd, 2017.

・Anggraeini Puspitasari, Hiroyuki Yamazaki, Hidemasa Kawamura, Akihisa Takahashi, Yukari Yoshida, Tomoaki Shirao, Takashi Nakano, Kathryn D Held. “X-irradiation of developing neurons causes delayed decrease in cell number and in synaptic related proteins of surviving neurons”. The 8th International Society of Radiation Neurobiology Conference, Tsukuba, Japan. February 9th – 10th, 2018.

・12/11/8-11/9, International Synapse Research Workshop 2012, Okazaki Aichi. [Acute effect of X-irradiation on adult mouse brain] as second author.

・13/1/25 – 1/26, The 3rd International Society of Radiation Neurobiology Conference, [Acute effect of X-irradiation on adult mouse brain].

・13/3/27 – 3/29, The 90th Annual meeting of the Physiological Society of Japan, Tokyo. [Acute effect of X-irradiation on adult mouse brain].

・13/4/20 – 4/24, 24th Meeting of the International Society for Neurochemistry ISN ASN Cancun, Mexico. [Acute effect of X-irradiation on adult mouse brain] as second author.

・13/6/20 – 6/23, Neuro 2013, Kyoto. [Effect of Irradiation on learning, cell death and synaptic proteins.]

・13/11/9 – 11/13, Society for Neuroscience 2013, San Diego, US. [Acute effects of X-irradiation on learning, adult neurogenesis and the accumulation of drebrin]

・14/09/11 – 09/13, The 37th Annual Meeting of the Japan Neuroscience Society. Neuroscience 2014, Yokohama, japan. [Acute effect of carbon ion irradiation on hippocampal neuronal cell death and fear memory formation].

・14/09/20 – 09/22, ISN Special Conference 2014, Tokyo, Japan. [Acute effect of Carbon ion irradiation on hippocampal neuron and fear memory formation].

・14/11/15 – 11/19, Society for Neuroscience 2014, Washington DC, US. [Acute effect of X-irradiation and carbon ion-irradiation on fear memory formation and its underlying mechanism].

・15/02/21, International Society of Radiation Neurobiology 5th Conference, Takasaki, Japan. [The irradiation effects on higher brain function with low LET radiation and high LET radiation].

・15/07/28 – 31, The 38th Annual Meeting of the Japan Neuroscience Society. Neuroscience 2015, Kobe, japan. [Acute effect of X-irradiation and Carbon ion-irradiation on fear memory formation].

・15/08/23 – 27, The 25th Meeting of the International Society for Neurochemistry, Cairns, Australia, ISN 2015 Biennial Meeting. [Transient effect of X-irradiation and Carbon ion-irradiation on synaptic function].

・The 6th International Society of Radiation Neurobiology Conference (ISRN-2016-Nagasaki, Japan). Anggraeini Puspitasari with the title [Irradiation effects on higher brain function with low and high LET radiation]. (invited), 2016

・The 58th Annual Meeting of the Japanese Society for Neurochemistry, Omiya, Saitama, Japan. Anggraeini Puspitasari, [The acute immediate effect of X-irradiation and Carbon ion irradiation on synaptic function and fear memory formation.], 2015

・The 62nd annual International Meeting Radiation Research Society, Waikoloa Village-Big Island, Hawaii. Anggraeini Puspitasari, Hidemasa Kawamura, Kathryn D. Held, Tomoaki Shirao, Takashi Nakano. [The radiation-induced bystander effects on synaptic function of mature neurons.],2016

・The 7th International Society of Radiation Neurobiology Conference on Feb 9-10, 2017; Acute and Chronic Effect of Low Dose X-irradiation on Immature Hippocampal Neurons In Vitro. Anggraeini Puspitasari, Akihisa Takahashi, Tomoaki Shirao, Takashi Nakano, Kathryn D Held.

・31st International Symposium on Space Technology and Science, Matsuyama, Japan, June 2017.Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, “Performance evaluation of new devices to synchronize X-ray or heavy-ion irradiation and simulated microgravity for space radiation research”,

・The 63rd annual International Meeting Radiation Research Society, Cancun, Mexico. October 15-18, 2017. Anggraeini Puspitasari, Akihisa Takahashi, Tomoaki Shirao, Takashi Nakano, Kathryn D Held. “Low Dose of X-irradiation on Immature Hippocampal Neurons (In Vitro) affecting number of neurons and drebrin clusters density”.

・Society for Neuroscience 2017, Washington, DC. Anggraeini Puspitasari, Noriko Koganezawa, Kathryn D. Held, Tomoaki Shirao, Takashi Nakano.  [Cell-cell communication may underlie radiation-induced synaptic dysfunction of mature neurons] . November 11th -15th, 2017.

*2017 – 2018 Granted research from KAKENHI; Grant-in-Aid for Young Scientists B category.
*2016 -2017 Grant in aid for Female researcher from Gunma University (FY) 2016 -2017; The role of astrocytes on synaptic dysfunction after radiation exposure.
*2012 – 2016; Scholarships from “The Program for Cultivating Global Leaders in Heavy Ion Therapeutics and Engineering”, Gunma University.
*2015; Gunma University Graduate School of Medicine, DEAN’S AWARD for an excellent presentation at Seminar for Presentation and Discussion. [The irradiation effects on higher brain function with electromagnetic radiation and particulate radiation], Gunma University.
*2015; Best Poster Presentation Award, “International Society of Radiation Neurobiology 5th Conference, Takasaki, Japan.” [The irradiation effects on higher brain function with low-LET radiation and high LET radiation], Gunma University.
*2015; Granted research from “The Program for Cultivating Global Leaders in Heavy Ion Therapeutics and Engineering”, Gunma University.
*2014; Best Presentation Award “The 2nd International Seminar of the Gunma University Program for Cultivating Global Leaders in Heavy Ion Therapeutic and Engineering”, with the title [Early effects of X-irradiation on learning and synaptic protein], Gunma University.
*2014; Granted research from “The Program for Cultivating Global Leaders in Heavy Ion Therapeutics and Engineering”, Gunma University.
*2013; Granted research from “The Program for Cultivating Global Leaders in Heavy Ion Therapeutics and Engineering”, Gunma University.

1 .12/9/18-9/21, 35th Japan Neuroscience 2012, Nagoya Japan.
2. 13/1/25 – 1/26, The 3rd International Society of Radiation Neurobiology Conference, [Acute effect of X-irradiation on adult mouse brain].
3. 13/3/27-3/29, The 90th Annual meeting of the Physiological Society of Japan, Tokyo. [Acute effect of X-irradiation on adult mouse brain].
4. 13/6/20-6/23, Neuro 2013, Kyoto. [Effect of Irradiation on learning, cell death and synaptic proteins.]
5. 13/11/9-11/13, Society for Neuroscience 2013. [Acute effects of X-irradiation on learning, adult neurogenesis and the accumulation of drebrin]
6. 14/03/23 – 03/27, Society of Toxicology 2014, Phoenix, Arizona.
7. 14/09/11 – 09/13, The 37th Annual Meeting of the Japan Neuroscience Society. Neuroscience 2014, Yokohama, japan. [Acute effect of carbon ion irradiation on hippocampal neuronal cell death and fear memory formation].
8. 14/09/20 – 09/22, ISN Special Conference 2014, Tokyo, Japan. [Acute effect of Carbon ion irradiation on hippocampal neuron and fear memory formation].
9. 14/11/15 – 11/19, Society for Neuroscience 2014, Washington DC, US. [Acute effect of X-irradiation and carbon ion-irradiation on fear memory formation and its underlying mechanism].
10. 15/02/21, International Society of Radiation Neurobiology 5th Conference, Takasaki, Japan. [The irradiation effects on higher brain function with low LET radiation and high LET radiation].
11. 15/07/28 – 31, The 38th Annual Meeting of the Japan Neuroscience Society. Neuroscience 2015, Kobe, japan. [Acute effect of X-irradiation and Carbon ion-irradiation on fear memory formation].
12. 15/08/23 – 27, The 25th Meeting of the International Society for Neurochemistry, Cairns, Australia, ISN 2015 Biennial Meeting. [Transient effect of X-irradiation and Carbon ion-irradiation on synaptic function].
13. 15/09/11 – 13, The 58th Annual Meeting of the Japanese Society for Neurochemistry, Omiya, Saitama, Japan. [The acute immediate effect of X-irradiation and Carbon ion-irradiation on synaptic function and fear memory formation.]
14. Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, Takahashi A, “Gene expression profile changes of human fibroblasts using device to synchronize carbon-ion irradiation and simulated microgravity”, The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), Suzhou, China, May 2017.
15. Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, “New devices to synchronize irradiation and simulated µG for space radiation research”, The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), Suzhou, China, May 2017.


池田 裕子
職名:研究員

主要実績(論文、学会発表、受賞など)

・Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T. Performance evaluation of new devices to synchronize heavy-ion or X-ray irradiation and simulated microgravity for space radiation research ~ Improvement of a control stage ~. The 31st International Symposium on Space Technology and Science (ISTS), proceeding, Theses ID: 2017-p-09.

・Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system. Life Sci. Space Res., 12:51-60, 2017.

・Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A. A new system for three-dimensional clinostat synchronized X-irradiation with a high-speed shutter for space radiation research. Biol. Sci. Space, 30:8-16, 2016.

・Yokota Y, Funayama T, Mutou-Yoshihara Y, Ikeda H, Kobayashi Y. The bystander cell-killing effect mediated by nitric oxide in normal human fibroblasts varies with irradiation dose but not with radiation quality. Int. J. Radiat. Biol., 91:383-388, 2015.

・Autsavapromporn N, Suzuki M, Funayama T, Usami N, Plante I, Yokota Y, Mutou Y, Ikeda H, Kobayashi K, Kobayashi Y, Uchihori Y, Hei TK, Azzam EI, Murakami T. Gap junction communication and the propagation of bystander effects induced by microbeam irradiation in human fibroblast cultures: the impact of radiation quality. Radiat. Res., 180:367-375, 2013.

・Wakabayashi N, Tsujino M, Tajiri M, Taki M, Kosino A, Ikeda H, Fukushima N, Tsujiuchi T. No mutations of lysophosphatidic acid receptor genes in lung adenocarcinomas induced by N-Nitrosobis (2-hydroxypropyl) amine in rats. J. Toxicol Pathol., 23(1): 63-66, 2010.

・Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Hada M, Saganti P, Yoshida Y, Kanai T, Takahashi A. “Development of 3D clinostat synchronized irradiation systems for simulating space conditions”, #18392, 2018 NASA Human Research Program Investigators’ Workshop, Texas, USA, January 2018.

・Ikeda H, Puspitasari A, Held KD, Yoshida Y, Takahashi A. “Importance of the combined effects of radiation and simulated microgravity for space biosciences”, 21st IAA Humans in Space Symposium, Shenzhen, China, November 2017.

・ 池田裕子, 想田光, 村谷匡史, Puspitasari Anggraeini, HELD Kathryn D, 日出間純, 吉田由香里, 金井達明, 髙橋昭久. “宇宙環境を模擬した疑似微小重力と重粒子線の複合影響による遺伝子発現解析”, 日本放射線影響学会第60回大会, 千葉, 2017年10月.

・池田裕子. 日本宇宙生物科学会平成29年度受賞記念講演 (奨励賞) “宇宙環境を模擬した微小重力下の放射線同期照射システムの開発”, 日本宇宙生物科学会31回大会, 前橋, 2017年9月.

・Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T. “Performance evaluation of new devices to synchronize X-ray or heavy-ion irradiation and simulated microgravity for space radiation research”, The 31st International Symposium on Space Technology and Science, Matsuyama, Japan, June 2017.

・Ikeda H, Muratani M, Puspitasari A, Held KD, Hidema J, Yoshida Y, Takahashi A. “Gene expression profile changes of human fibroblasts using device to synchronize carbon-ion irradiation and simulated microgravity”, The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), Suzhou, China, May 2017.

・Takahashi A, Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T. “New devices to synchronize irradiation and simulated µG for space radiation research”, The 5th International Symposium on Space Radiation and Particle Radiotherapy, including the 8th International Workshop on Space Research Radiation (IWSRR) and the 17th Ion Beams in Biology and Medicine (IBIBAM), Suzhou, China, May 2017.

・[Invited seminar] Ikeda H. “Comprehensive gene expression analysis of human fibroblasts using new device to synchronize carbon-ion irradiation and simulated microgravity” at Prairie View A&M University (CRI/RaISE Science seminar), Texas, USA, January 2018.

・Ikeda H. Support of dispatching young researchers abroad from “Living in Space”, 5 years’ fund of “Grant-in-Aid for scientific Research on Innovative Area (2015-2019) from Ministry of Education, Culture, Sports, Science and Technology Japan (MEXT), Texas, USA, January 15-31, 2018.

・Ikeda H. The Award for Young Investigator of the Japanese Society for Biological Sciences in Space. September 2017.

・Ikeda H. Support project of research for thesis in Fiscal Year 2014: Financial support for participating in “2015 Radiation Epidemiology and Dosimetry Course” at the National Cancer Institute, Rockville, MD, USA, 2015.

・ Ikeda H. Support project of research for thesis in Fiscal Year 2014: Supporting for PhD student, 2014-2015.

・Ikeda H. Award for Emerging Technology. 11th Young Researcher’s Presentation and Discussion Meeting, Atomic Energy Society of Japan, Kanto-Koetsu Branch, 2012.

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