Brief History

Related Websites

Main Achievements

Papers

• DNA barcoding and gene expression recording reveal the presence of cancer cells with unique properties during tumor progression.
  Yuka Umeki, Noriaki Ogawa, Yuko Uegaki, Kotaro Saga, Yasufumi Kaneda, Keisuke Nimura(corresponding author),
  Cellular and molecular life sciences : CMLS 80(1) 17-17, 2022 Dec 23.
• Dual function of SF3B2 on chromatin and RNA to regulate transcription in head and neck squamous cell carcinoma.
  Koji Kitamura*, Hidefumi Suzuki, Ryota Abe, Hidenori Inohara, Yasufumi Kaneda, Hidehisa Takahashi, Keisuke Nimura* (corresponding author), (*, co-first)
  Cell & bioscience 12(1) 92-92, 2022 Jun 17.
• NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis.
  Saga K, Park J, Nimura K, Kawamura N, Ishibashi A, Nonomura N, Kaneda Y,
  Journal of experimental & clinical cancer research: CR 38(1) 416, 2019 Oct.
• SF3B2-mediated RNA splicing drives human prostate cancer progression.
  Norihiko Kawamura*, Keisuke Nimura* (co-first, corresponding author), Kotaro Saga, Airi Ishibashi, Koji Kitamura, Hiromichi Nagano, Yusuke Yoshikawa, Kyoso Ishida, Norio Nonomura, Mitsuhiro Arisawa, Jun Luo, Yasufumi Kaneda,
  Cancer Research 79(20) 5204-5217, 2019 Oct 15.
• Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.
  Kyong-Rim Kieffer-Kwon*, Keisuke Nimura*, Suhas S. P. Rao*, Jianliang Xu*, Seolkyoung Jung, Aleksandra Pekowska, Marei Dose, Evan Stevens, Ewy Mathe, Peng Dong, Su-Chen Huang, Maria Aurelia Ricci, Laura Baranello, Ying Zheng, Francesco Tomassoni Ardori, Wolfgang Resch, Diana Stavreva, Steevenson Nelson, Michael McAndrew, Adriel Casellas, Elizabeth Finn, Charles Gregory, Brian Glenn St Hilaire, Steven M. Johnson, Wendy Dubois, Maria Pia Cosma, Eric Batchelor, David Levens, Robert D. Phair, Tom Misteli, Lino Tessarollo, Gordon Hager, Melike Lakadamyali, Zhe Liu, Monique Floer, Hari Shroff, Erez Lieberman Aiden, Rafael Casellas, (*, co-first)
  MOLECULAR CELL 67(4) 566, 2017 Aug.
• Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development.
  Keisuke Nimura (corresponding author), Masamichi Yamamoto, Makiko Takeichi, Kotaro Saga, Katsuyoshi Takaoka, Norihiko Kawamura, Hirohisa Nitta, Hiromichi Nagano, Saki Ishino, Tatsuya Tanaka, Robert J Schwartz, Hiroyuki Aburatani, Yasufumi Kaneda,
  eLife 5, 2016 Jun 22.
• WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition.
  Naoyuki Sarai, Keisuke Nimura, Tomohiko Tamura, Tomohiko Kanno, Mira C. Patel, Tom D. Heightman, Kiyoe Ura, Keiko Ozato
  EMBO JOURNAL 32(17) 2392-2406, 2013 Aug.
• DNA methyltransferase 3b preferentially associates with condensed chromatin.
  Katsunobu Kashiwagi, Keisuke Nimura, Kiyoe Ura, Yasufumi Kaneda
  NUCLEIC ACIDS RESEARCH 39(3) 874-888, 2011.Feb.
• A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome.
  Keisuke Nimura, Kiyoe Ura, Hidetaka Shiratori, Masato Ikawa, Masaru Okabe, Robert J. Schwartz, Yasufumi Kaneda,
  NATURE 460(7252) 287-U157, 2009 Jul.
• Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation
  Keisuke Nimura, Chisaki Ishida, Hiroshi Koriyama, Kenichiro Hata, Shinya Yamanaka, En Li, Kiyoe Ura, Yasufumi Kaneda
  GENES TO CELLS 11(10) 1225-1237, 2006 Oct.

Awards