Gunma University Initiative for Advanced Research > About GIAR > Members > Gene Therapy Science > Dr. Yokobori Laboratory > Andrei TURTOI


Brief History

January 2020 – Present “Montpellier Alliance for Metabolomics and Metabolism Analysis”, Biocampus Metabolomics Platform, INSERM, CNRS, University of Montpellier, France. Scientific Director
November 2016 – Present “Tumor Microenvironment and Resistance to Treatment”, Institut de Recherche en Cancérologie de Montpellier (IRCM), Montpellier, France Team Leader
September 2016 – Present École Nationale Supérieure de Chimie de Montpellier (ENSCM), Montpellier,France.Lecturer
May 2015 – Present Gunma University Initiative for Advanced Research (GIAR), Graduate School of Medicine, University of Gunma, Maebashi, Japan. Invited Lecturer
May 2015 Faculty of Medicine/ GIGA-Cancer, Metastasis Research Laboratory, University of Liege, Liege, Belgium
FNRS Scientific Collaborator (Televie Fellowship),
2012 Faculty of Medicine/ GIGA-Cancer, Metastasis Research Laboratory,
University of Liege, Liege, Belgium FNRS Charge de Recherché,
2009 Faculty of Medicine/ GIGA-Cancer, Metastasis Research Laboratory, University of Liege, Liege, Belgium
Principal Investigator,
2008 Faculty of Sciences/ Department of Chemistry, Mass Spectrometry Laboratory, University of Liege, Liege, Belgium Postdoctoral Fellow

Main Achievements


  • Souche R, Tosato G, Rivière B, Valats JC, Debourdeau A, Flori N, Pourquier D, Fabre JM, Assenat E, Colinge J, Turtoi A. Detection of soluble biomarkers of pancreatic cancer in endoscopic ultrasound-guided fine-needle aspiration samples. Endoscopy. 2022 May;54(5):503-508. doi: 10.1055/a-1550-2503. Epub 2021 Aug 26. PMID: 34448184.
  • Chiavarina B, Ronca R, Otaka Y, Sutton RB, Rezzola S, Yokobori T, Chiodelli P, Souche R, Pourquier D, Maraver A, Faa G, Khellaf L, Turtoi E, Oyama T, Gofflot S, Bellahcène A, Detry O, Delvenne P, Castronovo V, Nishiyama M, Turtoi A. Fibroblast-derived prolargin is a tumor suppressor in hepatocellular carcinoma. Oncogene. 2022 Mar;41(10):1410-1420. doi: 10.1038/s41388-021-02171-z. Epub 2022 Jan 14. PMID: 35031773.
  • Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N. STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses. Cell Metab. 2022 Jan 4;34(1):125-139.e8. doi:10.1016/j.cmet.2021.12.007. PMID: 34986331; PMCID: PMC8733004.
  • Chiavarina B, Costanza B, Ronca R, Blomme A, Rezzola S, Chiodelli P, Giguelay A, Belthier G, Doumont G, Van Simaeys G, Lacroix S, Yokobori T, Erkhem-Ochir B, Balaguer P, Cavailles V, Fabbrizio E, Di Valentin E, Gofflot S, Detry O, Jerusalem G, Goldman S, Delvenne P, Bellahcène A, Pannequin J, Castronovo V, Turtoi A. Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis. Theranostics. 2021 Jan 1;11(4):1626-1640. doi:
    10.7150/thno.51507. PMID: 33408771; PMCID: PMC7778592.
  • Alame M, Cornillot E, Cacheux V, Tosato G, Four M, De Oliveira L, Gofflot S, Delvenne P, Turtoi E, Cabello-Aguilar S, Nishiyama M, Turtoi A, Costes-Martineau V, Colinge J. The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities. Theranostics. 2020 Mar 15;10(10):4383-4394. doi: 10.7150/thno.42986. PMID: 32292502; PMCID: PMC7150470.
  • Nakazawa N, Yokobori T, Kaira K, Turtoi A, Baatar S, Gombodorj N, Handa T, Tsukagoshi M, Ubukata Y, Kimura A, Kogure N, Ogata K, Maeno T, Sohda M, Yajima T, Shimizu K, Mogi A, Kuwano H, Saeki H, Shirabe K. High Stromal TGFBI in Lung Cancer and Intratumoral CD8-Positive T Cells were Associated with Poor Prognosis and Therapeutic Resistance to Immune Checkpoint Inhibitors. Ann Surg Oncol. 2020 Mar;27(3):933-942. doi: 10.1245/s10434-019-07878-8. Epub 2019 Sep 30. PMID:31571056.


2017-2022 Prime d’Encadrement Doctoral et de Recherche, INSERM, France.
2016 Hans-Monga Award for Excellence in Neoplasia Research, ASIP, Bethesda, MD, USA.
2015 Special Award of the Friends of University of Liege, Liege, Belgium.
2015 Research Award of the Belgian Group of Digestive Oncology, Brussels, Belgium.
2014 Nicolas Jacquet Award, Leon Fredericq Fund, Liege, Belgium.
2014 Merit Award, American Society for Investigative Pathology (ASIP), Bethesda, MD, USA