Main Achievements
2021
- Yoshida, T; Yokobori, T; Saito, H; Kuriyama, K; Kumakura, Y; Honjo, H; Hara, K; Sakai, M; Miyazaki, T; Obinata, H; Erkhem-Ochir, B; Gombodorj, N; Sohda, M; Saeki, H; Kuwano, H; Shirabe, K CD36 Expression Is Associated with Cancer Aggressiveness and Energy Source in Esophageal Squamous Cell Carcinoma. ANNALS OF SURGICAL ONCOLOGY. 2021 Feb; 28(2): 1217-1227.
- Bilguun Erkhem-Ochir MD, Wataru Tatsuishi MD,PhD, Takehiko Yokobori MD, PhD,Tsukasa Ohno MD, PhD, KyoheiHatori MD, PhD, Tadashi Handa PhD,Tetsunari Oyama MD, PhD, Ken Shirabe, MD, PhD, Hiroshi Saeki MD,PhD, Tomonobu Abe MD, PhD Inflammatory and immune checkpoint markers are associated with the severity of aortic stenosis. JTCVS. 2021 Jan.
- Chiavarina, B; Costanza, B; Ronca, R; Blomme, A; Rezzola, S; Chiodelli, P; Giguelay, A; Belthier, G; Doumont, G; Van Simaeys, G; Lacroix, S; Yokobori, T; Erkhem-Ochir, B; Balaguer, P; Cavailles, V; Fabbrizio, E; Di Valentin, E; Gofflot, S; Detry, O; Jerusalem, G; Goldman, S; Delvenne, P; Bellahcene, A; Pannequin, J; Castronovo, V; Turtoi, A Metastatic colorectal cancer cells maintain the TGF beta program and use TGFBI to fuel angiogenesis. THERANOSTICS. 2021 Jan; 11(4): 1626-1640.
2020
- Kuwano, H; Yokobori, T; Kumakura, Y; Ogata, K; Yoshida, T; Kuriyama, K; Sakai, M; Sohda, M; Miyazaki, T; Saeki, H; Shirabe, K Pathophysiology of Vomiting and Esophageal Perforation in Boerhaave’s Syndrome. DIGESTIVE DISEASES AND SCIENCES. 2020. Nov; 65(11): 3253-3259.
- Dolgormaa, G; Harimoto, N; Ishii, N; Yamanaka, T; Hagiwara, K; Tsukagoshi, M; Igarashi, T; Watanabe, A; Kubo, N; Araki, K; Handa, T; Yokobori, T; Oyama, T; Kuwano, H; Shirabe, K Mac-2-binding protein glycan isomer enhances the aggressiveness of hepatocellular carcinoma by activating mTOR signaling. BRITISH JOURNAL OF CANCER. 2020 Sep 29; 123(7): 1145-1153.
- Kubo, N; Yokobori, T; Takahashi, R; Ogawa, H; Gombodorj, N; Ohta, N; Ohno, T; Saeki, H; Shirabe, K; Asao, T An abdominal spacer that does not require surgical removal and allows drainage of abdominal fluids in patients undergoing carbon ion radiotherapy. PLOS ONE. 2020 Jun 10; 15(6): e0234471.
- Kuriyama, K; Higuchi, T; Yokobori, T; Saito, H; Yoshida, T; Hara, K; Suzuki, S; Sakai, M; Sohda, M; Higuchi, T; Tsushima, Y; Asao, T; Kaira, K; Kuwano, H; Shirabe, K; Saeki, H Uptake of positron emission tomography tracers reflects the tumor immune status in esophageal squamous cell carcinoma. CANCER SCIENCE. 2020 Jun; 111(6): 1969-1978.
- Baatar, S; Bai, T; Yokobori, T; Gombodorj, N; Nakazawa, N; Ubukata, Y; Kimura, A; Kogure, N; Sano, A; Sohda, M; Sakai, M; Tumenjargal, A; Ogata, K; Kuwano, H; Shirabe, K; Saeki, H High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer. ANNALS OF SURGICAL ONCOLOGY. 2020 Oct; 27(11): 4360-4368.
- Togo, M; Yokobori, T; Shimizu, K; Handa, T; Kaira, K; Sano, T; Tsukagoshi, M; Higuchi, T; Yokoo, S; Shirabe, K; Oyama, T Diagnostic value of F-18-FDG-PET to predict the tumour immune status defined by tumoural PD-L1 and CD8(+)tumour-infiltrating lymphocytes in oral squamous cell carcinoma. BRITISH JOURNAL OF CANCER. 2020 May 26; 122(11): 1686-1694.
- Hagiwara, K; Harimoto, N; Yokobori, T; Muranushi, R; Hoshino, K; Gantumur, D; Yamanaka, T; Ishii, N; Tsukagoshi, M; Igarashi, T; Tanaka, H; Watanabe, A; Kubo, N; Araki, K; Hosouchi, Y; Shirabe, K High Co-expression of Large Tenascin C Splice Variants in Stromal Tissue and Annexin A2 in Cancer Cell Membranes is Associated with Poor Prognosis in Pancreatic Cancer. ANNALS OF SURGICAL ONCOLOGY. 2020 Mar; 27(3): 924-930.
- Yamanaka, T; Harimoto, N; Yokobori, T; Muranushi, R; Hoshino, K; Hagiwara, K; Gantumur, D; Handa, T; Ishii, N; Tsukagoshi, M; Igarashi, T; Tanaka, H; Watanabe, A; Kubo, N; Araki, K; Shirabe, K Nintedanib inhibits intrahepatic cholangiocarcinoma aggressiveness via suppression of cytokines extracted from activated cancer-associated fibroblasts. BRITISH JOURNAL OF CANCER. 2020 Mar; 122(7): 986-994.
2019
Shimizu K, Goto Y, Kawabata-Iwakawa R, Ohtaki Y, Nakazawa S, Yokobori T, Obayashi K, Kawatani N, Yajima T, Kaira K, Mogi A, Hirato J, Nishiyama M, Shirabe K. Stathmin-1 is a useful diagnostic marker for high-grade lung neuroendocrine tumors. Ann Thorac Surg. 2019 Mar 22. pii: S0003-4975(19)30392-3.
2018
Suzuki K, Watanabe A, Araki K, Yokobori T, Harimoto N, Gantumur D, Hagiwara K, Yamanaka T, Ishii N, Tsukagoshi M, Igarashi T, Kubo N, Gombodorj N, Nishiyama M, Hosouchi Y, Kuwano H, Shirabe K. High STMN1 Expression Is Associated with Tumor Differentiation and Metastasis in Clinical Patients with Pancreatic Cancer. Anticancer Res. 2018 Feb;38(2):939-944.
2017
- Bao P, Yokobori T, Altan B, Iijima M, Azuma Y, Onozato R, Yajima T, Watanabe A, Mogi A, Shimizu K, Nagashima T, Ohtaki Y, Obayashi K, Nakazawa S, Bai T, Kawabata-Iwakawa R, Asao T, Kaira K, Nishiyama M, Kuwano H. High STMN1 Expression is Associated with Cancer Progression and Chemo-Resistance in Lung Squamous Cell Carcinoma. Ann Surg Oncol. 2017 Dec;24(13):4017-4024.
- Obayashi S, Horiguchi J, Higuchi T, Katayama A, Handa T, Altan B, Bai T, Bao P, Bao H, Yokobori T, Nishiyama M, Oyama T, Kuwano H. Stathmin1 expression is associated with aggressive phenotypes and cancer stem cell marker expression in breast cancer patients. Int J Oncol. 2017 Sep;51(3):781-790.
- Shimizu K, Ohtaki Y, Altan B, Yokobori T, Nagashima T, Arai M, Mogi A, Kuwano H. Prognostic impact of stathmin 1 expression in patients with lung adenocarcinoma. J Thorac Cardiovasc Surg. 2017 Oct;154(4):1406-1417.e3.
- Watanabe A, Araki K, Yokobori T, Altan B, Ishii N, Tsukagoshi M, Kubo N, Saito F, Suzuki H, Kuwano H. Stathmin 1 promotes the proliferation and malignant transformation of pancreatic intraductal papillary mucinous neoplasms. Oncol Lett. 2017 Mar;13(3):1783-1788.
- Suzuki S, Yokobori T, Altan B, Hara K, Ozawa D, Tanaka N, Sakai M, Sano A, Sohda M, Bao H, Fukuchi M, Miyazaki T, Kaira K, Asao T, Kuwano H. High stathmin 1 expression is associated with poor prognosis and chemoradiation resistance in esophageal squamous cell carcinoma. Int J Oncol. 2017 Mar 7.
- Bai T, Yokobori T, Altan B, Ide M, Mochiki E, Yanai M, Kimura A, Kogure N, Yanoma T, Suzuki M, Bao P, Kaira K, Asao T, Katayama A, Handa T, Gombodorj N, Nishiyama M, Oyama T, Ogata K, Kuwano H. High STMN1 level is associated with chemo-resistance and poor prognosis in gastric cancer patients. Br J Cancer. 2017 Apr 25;116(9):1177-1185.
2016
Saito F, Araki K, Yokobori T, Ishii N, Tsukagoshi M, Watanabe A, Kubo N, Altan B, Shirabe K, Kuwano H. High expression of karyopherin-α2 and stathmin 1 is associated with proliferation potency and transformation in the bile duct and gall bladder epithelia in the cases of pancreaticobiliary maljunction. J Surg Oncol. 2016 Sep;114(4):462-8.
2014
Watanabe A, Suzuki H, Yokobori T, Tsukagoshi M, Altan B, Kubo N, Suzuki S, Araki K, Wada S, Kashiwabara K, Hosouchi Y, Kuwano H. Stathmin1 regulates p27 expression, proliferation and drug resistance, resulting in poor clinical prognosis in cholangiocarcinoma. Cancer Sci. 2014 Jun;105(6):690-6.